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Precision Genomic Risk Intelligence for Europe
Starling Genomics delivers clinically robust polygenic risk scores designed for scalable deployment across European healthcare systems.
A European Genomics Platform Company
Starling Genomics develops and deploys validated polygenic risk score solutions for healthcare systems, laboratories, and clinical partners across Europe.
We combine scalable PRS engine infrastructure with regulatory-aware implementation strategies to enable responsible integration of genomic risk insights into clinical pathways.
From Genetic Data to Quantified Risk
The platform follows a structured five-stage PRS engine flow designed for clinical traceability and operational deployment in healthcare environments.
- Step 1 Sample collection and genomic processing in controlled laboratory settings.
- Step 2 Secure VCF data ingestion through governance-defined interfaces.
- Step 3 Polygenic risk score calculation using validated computational models.
- Step 4 Risk estimation and structured reporting suitable for clinical interpretation.
- Step 5 Integration into healthcare workflows, calculators, and care pathways.
Scalable PRS Engine Architecture
Starling Genomics provides a deployment-oriented architecture built for healthcare institutions that require reproducibility, data security, and interoperability.
- Designed for deployment within national or regional domains
- Secure genomic data ingestion with VCF-based workflows
- Risk estimation algorithms calibrated against large-scale biobank validation datasets
- Modular disease portfolio for phased implementation planning
- Integration-ready outputs for clinical calculators and care pathway tools
Implementation Focus
The operating model is built for institutional adoption: transparent score generation logic, auditable reporting pipelines, and governance controls compatible with European clinical and data frameworks.
Technical integration can be configured for laboratory-first or care pathway-first deployments, depending on partner infrastructure.
Polygenic Risk Score Portfolio
The portfolio is organized by clinical domain to support phased deployment, evidence review, and country-specific implementation planning.
Cardiometabolic
- Cardiovascular disease
- Coronary artery disease
- Hypertension
- Atrial fibrillation
- Type 2 diabetes
- Chronic kidney disease
- Ischemic stroke
Oncology
Core oncology-focused PRS modules are available for staged clinical program design.
Neurology & Psychiatry
Risk models are available for integration into broader neurological and psychiatric pathway assessments.
Immunology & Inflammation
Domain modules support investigation of inflammatory and immune-mediated risk stratification.
Ophthalmology
- Age-related macular degeneration
- Primary open angle glaucoma
Bone Health
Polygenic modules support risk profiling in bone density and fracture-related contexts.
Gastroenterology
Selected PRS modules are designed for gastroenterology-oriented risk characterization.
Quantitative Traits
Quantitative trait models support research-to-clinic transition and integrated risk interpretation.
Polygenic risk scores provide probabilistic risk information and are not diagnostic tests.
European Rollout Strategy
Starling Genomics is deploying its PRS platform across selected European markets, beginning with the Netherlands.
Modular Platform Extensions
The platform structure is prepared for additional modules as implementation programs expand.
Laboratory Partner Layer
Standardized onboarding interfaces for laboratory integration workflows.
White Papers
Evidence summaries and technical documentation publication module.
Regulatory Documentation
Governance and compliance artifact repository for local jurisdictions.